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Nutrition and Ultrastructure of the Mutants of Methylotrophic Yeasts Defective in Biogenesis and Degradation of Peroxisomes

Aleksander .R. Kulackovsky 1, Oleg V. Stasye, Halyna P. Ksheminska2, Litibov R. Fayura2, Oksana M. Moraz1 and Andrii A. Sibirny2,3*


1
Franko Lviv State University, Hrushevsky Street, 4, Lviv 290005, Ukraine
2
Lviv Division of Institute of Biochemistry, Drahomanov Street, 14/16, Lviv 290005, Ukraine

3
Czestochowa Technical University, Dabrowskiego 69, Czestochowa 42-201, Poland


Article history:

Received August 1, 1997

Accepted January 15, 1998

Key words:

methylotrophic yeasts, ultrastructu re, peroxisomes, biogenesis, autophagy

Summary:

The demand for natural food colourants is increasing because of public awareness of their health benefits. Betalains are nitrogen-containing plant pigments whose colours range from red-violet betacyanins to yellow betaxanthins. They are used for colouring dairy products, meat and frozen desserts. Betalains have attracted additional interest because of their antioxidative, anti-inflammatory and anticarcinogenic properties. The main source of commercially produced betalains is red beet root, but alternative sources are found in plants from the Amaranthaceae and Cactaceae families. Another alternative source is plant cell culture in bioreactors, although optimization of pigment production seems necessary. In this paper we synthesize the results of recent studies on betalain biosynthesis, chemical properties, sources, biotechnology and applications.



*Corresponding author:           sibirny@biochem.Lviv.ua
                                               380-322-740363
                                               380-322-721648

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