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Advances in Research of Polysaccharides in Cordyceps Species

Shi Zhong1, Huijuan Pan2, Leifa Fan2*, Guoying Lv2, Yongzhi Wu2, Binod Parmeswaran3, Ashok Pandey3 and Carlos Ricardo Soccol4


1Institute of Sericulture, Zhejiang Academy of Agricultural Sciences, CN-310021 Hangzhou, PR China

2Institute of Horticulture, Zhejiang Academy of Agricultural Sciences, CN-310021 Hangzhou, PR China
3Biotechnology Division, National Institute for Interdisciplinary Science and Technology (Formerly Regional Research Laboratory), IN-695019 Trivandrum, India
4Department of Chemical Engineering, Federal University of Parana, Centro Politecnico, Jardim das Americas, BR-81531-970 Curitiba-PR, Brazil

Article history:

Received April 10, 2008
Accepted March 19, 2009

Key words:

Cordyceps polysaccharide, production and purification, structure elucidation, pharmacological action

Summary:

Cordyceps sinensis (Berk.) Sacc. is one of the well-described fungi that has been used in traditional Chinese medicine for over 700 years. Fungal mycelia contain some polysaccharides that are responsible for their biological activity. C. sinensis has traditionally been cultivated on the high Tibetan plateau as a parasitic fungus growing on caterpillars. However, currently it is being cultivated on some insects and in artificial media. This article deals with the advances in the production, isolation and purification of Cordyceps polysaccharide (CP) in recent years, as well as the structure elucidation and pharmacological action. The article also aims to provide some references for further application and exploitation in the future.

 


*Corresponding author:           fanleifa@yahoo.com.cn
                                               ++86 571 8640 4319
                                               ++86 571 8640 4319

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