getpdf NLM PubMed Logo https://doi.org/10.17113/ftb.59.04.21.7223  

Detection of Microorganisms Using Graphene-Based Nanobiosensors

Mehrab Pourmadadi1, Fatemeh Yazdian1*, Sara Hojjati2 and Kianoush Khosravi-Darani3*orcid tiny

1School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran

2Department of Life Science Engineering, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran

3Department of Food Technology Research, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Science, P. O. Box 19395-4741, Tehran, Iran

Article history:

Received: 8 March 2021

Accepted: 19 October 2021

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Key words:

graphene, graphene oxide, reduced graphene oxide, graphene quantum dots, microorganism detection, nanobiosensors

Summary:

Having an insight into graphene and graphene derivatives such as graphene oxide, reduced graphene oxide and graphene quantum dot structures is necessary since it can help scientists to detect the possible properties and features that using these carbon materials in preparation of a nanocomposite could bring out. In recent years, graphene and its derivatives are attractive with extensive applications in biosensors due to fascinating properties, such as high surface area, optical and magnetic properties, and high elasticity for the detection of microorganisms can be modified with some other materials such as macromolecules, oxide metals, and metals to improve the electrochemical behaviour of the biosensor, and also can be modified with some other materials such as macromolecules, oxide metals, and metals to improve the electrochemical behaviour of the biosensor. In this review paper, biosensor design strategies based on graphene and its derivatives (graphene-based nanocomposites in biosensors) are introduced. Then, their application for the detection of microorganisms including prions, viroids, viral and bacterial cells as well as fungi, protozoa, microbial toxins, and even microbe-derived antibiotics are reviewed.

*Corresponding author: +982122086348
  +982122376473
  yazdian@ut.ac.ir; k.khosravi@sbmu.ac.ir

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