Potentiometric and Nanogravimetric Biosensors for Drug Screening and Pollutants Detection

Manuela Adami1, M. Sartore1 and Claudio Nicolini2

1Technobiochip, Via della Marina, 57030 Marciano (LI), Italy
2 Institute of Biophysics, University of Genova, Via Giotto, 2, 16153 Genova, Italy

Article history:

Received  May 24, 1996
Accepted  August 14, 1996

Key words:

biosensors, drug screening, pollutants detection, potentiometric and nanogravimetric transducing mechanisms

Recent advances in the field of biosensors are presented along with a few significant examples of their applications in the fields of health and environmental monitoring. In particular this paper focuses on two distinct biosensing systems based on potentiometric and gravimetric tranducers, These biosystems are here exemplifield in monitoring the effects of drugs on living cells and the kinetic monitoring of binding in the antigens-antibodies immunoreactions. The results demonstrate the significance and potential importance of these biosensors.

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