Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms

1Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, Croatia

2Institute of Biomedical Sciences, University of São Paulo, São Paulo SP-CEP 05508-900, Brasil
3King’s College, University of London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
4Department of Genetics, University of Kaiserslautern, Postfach 3049, DE-67653 Kaiserslautern, Germany

Article history:

Received October 3, 2012
Accepted January 18, 2013

Key words:

molecular biotechnology, industrial microorganisms, DNA synthesis, homologous recombination, recombinant gene clusters


The recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmental protection. In this minireview, the current state of the field is described and the role of synthetic biology in biotechnology in the short and medium term is discussed. It is particularly aimed at the needs of food technologists, nutritionists and other biotechnologists, who might not be aware of the potential significance of synthetic biology to the research and development in their fields. The potential of synthetic biology to produce interesting new polyketide compounds is discussed in detail. 

*Corresponding author: 
                                               +385 1 4605 013
                                               +385 1 4836 083

Search FTB

Follow us

 facebook 1 twitter bird_icon LI In Bug


Environmental Policy

sdg publishers compact 4 300x300

QR Code


We use cookies to improve our website and your experience when using it. Cookies used for the essential operation of the site have already been set. To find out more about the cookies we use and how to delete them, see our privacy policy.

I accept cookies from this site.

EU Cookie Directive Module Information