Tween® 20-Enhanced Bioreduction of Acetophenones Promoted by Daucus carota Root
Center for Natural Sciences and Humanities, Federal University of ABC – UFABC, Av. dos Estados 5001, CEP 09210-580, Santo André, SP, Brazil
Received May 13, 2016
Accepted March 16, 2017
biocatalysis, carrot root, surfactants, chiral alcohols
The effect of surfactants on the bioreduction of acetophenones mediated by carrot (Daucus carota) root was investigated. Among the tested surfactants, Tween® 20 slightly improved the conversion. The amount of surfactant was optimised, and the presented methodology was applied to other substituted acetophenones, which led to the preparation of their respective optically enriched 1-phenylethanols with high conversion levels and high enantioselectivities.
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