Yeast Genetics in Analysis of the Organization of Eucaryotic Genomes

Zoran Zgaga

Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 41 000 Zagreb, Croatia

Article history:
Received June 17, 1994
Accepted September 26, 1994

Summary:
Further progress in genetic manipulation of eucaryotes will depend largely on our understanding of the structure, organization and dynamics of eucaryotic genomes. Although the size of its genome is only about 0.5 % of the size of the human genome, the yeast Saccharomyces cerevisiae has a remarkable place in these studies. It is not only an important model organism but is also used as a tool in the analysis of different complex genomes, including human. Genomic projects performed with yeast, like the whole genome sequencing, are also an important example for the organization of similar investigations in other organisms.