Oxidoreductases from Trametes spp. in Biotechnology: A Wealth of Catalytic Activity
Gibson S. Nyanhongo1, Georg Gübitz1, Prakit Sukyai2,3, Christian Leitner2, Dietmar Haltrich2 and Roland Ludwig2,4*
1Department of Environmental Biotechnology, Graz University of Technology, Petersgasse 12, A-8010 Graz, Austria
2Department of Food Sciences and Technology, Division of Food Biotechnology, BOKU-University for Natural Resources and Applied Life Sciences, Muthgasse 18, A-1190 Vienna, Austria
3Faculty of Medicine, Kasetsart University, Phaholyotin Road, Chatujak Bangkok 10900, Thailand
4Research Centre Applied Biocatalysis, Petersgasse 14, A-8010 Graz, Austria
Article history:
Received September 13, 2006
Accepted May 4, 2007
Key words:
Trametes, laccase, cellobiose dehydrogenase, pyranose 2-oxidase, biodegradation, biosensors, biotechnology, food technology
Summary:
Those oxidoreductases that are part of the ligninolytic complex of basidiomycete and ascomycete fungi have played an increasingly important role in biotechnological applications during the last decade. The stability of these extracellular enzymes, their good solubility, and a multitude of catalyzed reactions contribute to this trend. This review focuses on a single genus of white-rot basidiomycetes, Trametes, to highlight the numerous possibilities for the application of this microorganism as well as three of its enzymes: laccase, cellobiose dehydrogenase, and pyranose 2-oxidase. Whereas laccase is without doubt a major player in biotechnology, the two other enzymes are less well known, but represent emerging biocatalysts with potential. Both cellobiose dehydrogenase and pyranose 2-oxidase are presumed to participate in lignin breakdown and will be used to exemplify the potential of less prominent oxidoreductases from this genus.
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