The Genetics and Molecular Biology of Flocculation in Saccharomyces cerevisiae: An Overview

C. Sieiro², N. M. Reboredo¹, P. Blanco¹, A. Diaz, T. G. Villa<sup>1

1</sup>Departamento de Microbiología. Facultad de Farrnacia. Universidad de Santiago de Curnpostela. Santiago de Compostela. Spain.
²Departamento do Biologia Funcional y Ciencias de la Salud. Area de Microbiología. Facultad de Ciencias. Universiclad de Vigo. Spain

Article history:
Received August 3, 2010
Accepted February 3, 2011

Key words:
flocculation, Saccharumyces cerevisiae, phenotype, genes, control of

Summary:
Floculalion in Sacch. cerevisiae is a process of reversible cellular aggregation. Their ability to flocculate enables efficient separation of cells from the fermentation medium and facilitates subsequent downstream processing of the product. The most important advances in our knowledge have been achieved about the mechanisms of flocculalion and its genetic bases. Recent advances in both fields are reviewed and some possible hints for the future are given.    

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